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client.chunkedgraph

Client for interacting with the chunkedgraph.

Methods:

Name Description
get_roots

Get the root ID for a list of supervoxels.

get_root_id

Get the root ID for a specified supervoxel.

get_minimal_covering_nodes

Get the minimal covering nodes for a list of root IDs.

get_merge_log

Get the merge log (splits and merges) for an object.

get_change_log

Get the change log (splits and merges) for an object.

get_user_operations

Get operation details for a user ID. Currently, this is only available to

get_tabular_change_log

Get a detailed changelog for neurons.

get_leaves_many

Get all supervoxels for a list of root IDs.

get_leaves

Get all supervoxels for a root ID.

do_merge

Perform a merge on the chunked graph.

undo_operation

Undo an operation.

execute_split

Execute a multicut split based on points or supervoxels.

preview_split

Get supervoxel connected components from a preview multicut split.

get_children

Get the children of a node in the chunked graph hierarchy.

get_contact_sites

Get contacts for a root ID.

find_path

Find a path between two locations on a root ID using the level 2 chunked

get_subgraph

Get subgraph of root id within a bounding box.

level2_chunk_graph

Get graph of level 2 chunks, the smallest agglomeration level above supervoxels.

remesh_level2_chunks

Submit specific level 2 chunks to be remeshed in case of a problem.

get_operation_details

Get the details of a list of operations.

get_lineage_graph

Returns the lineage graph for a root ID, optionally cut off in the past or

get_latest_roots

Returns root IDs that are related to the given root_id at a given

get_original_roots

Returns root IDs that are the latest successors of a given root ID.

is_latest_roots

Check whether these root IDs are still a root at this timestamp.

suggest_latest_roots

Suggest latest roots for a given root id, based on overlap of component

is_valid_nodes

Check whether nodes are valid for given timestamp range.

get_root_timestamps

Retrieves timestamps when roots where created.

get_past_ids

For a set of root IDs, get the list of IDs at a past or future time point

get_delta_roots

Get the list of roots that have changed between timetamp_past and

get_oldest_timestamp

Get the oldest timestamp in the database.

Attributes:

Name Type Description
server_version Optional[Version]

The version of the service running on the remote server. Note that this

timestamp Optional[datetime]

The default timestamp for queries which expect a timestamp. If None, uses the

segmentation_info

Complete segmentation metadata

base_resolution

MIP 0 resolution for voxels assumed by the ChunkedGraph

server_version: Optional[Version] property

The version of the service running on the remote server. Note that this refers to the software running on the server and has nothing to do with the version of the datastack itself.

timestamp: Optional[datetime.datetime] property writable

The default timestamp for queries which expect a timestamp. If None, uses the current time.

segmentation_info property

Complete segmentation metadata

base_resolution property

MIP 0 resolution for voxels assumed by the ChunkedGraph

Returns:

Type Description
list

3-long list of x/y/z voxel dimensions in nm

get_roots(supervoxel_ids, timestamp=None, stop_layer=None)

Get the root ID for a list of supervoxels.

Parameters:

Name Type Description Default
supervoxel_ids list or np.array of int

Supervoxel IDs to look up.

required
timestamp datetime

UTC datetime to specify the state of the chunkedgraph at which to query, by default None. If None, uses the timestamp property for this client, which defaults to the current time.

None
stop_layer int or None

If True, looks up IDs only up to a given stop layer. Default is None.

None

Returns:

Type Description
np.array of np.uint64

Root IDs containing each supervoxel.

get_root_id(supervoxel_id, timestamp=None, level2=False)

Get the root ID for a specified supervoxel.

Parameters:

Name Type Description Default
supervoxel_id int

Supervoxel id value

required
timestamp datetime

UTC datetime to specify the state of the chunkedgraph at which to query, by default None. If None, uses the timestamp property for this client, which defaults to the current time.

None

Returns:

Type Description
int64

Root ID containing the supervoxel.

get_minimal_covering_nodes(node_ids)

Get the minimal covering nodes for a list of root IDs.

Parameters:

Name Type Description Default
nodes_ids Iterable of int or np.int64

List of root IDs to query.

required

Returns:

Type Description
np.array of np.int64:

List of PCG node_ids that minimally and exactly cover the input nodes

get_merge_log(root_id)

Get the merge log (splits and merges) for an object.

Parameters:

Name Type Description Default
root_id int

Object root ID to look up.

required

Returns:

Type Description
list

List of merge events in the history of the object.

get_change_log(root_id, filtered=True)

Get the change log (splits and merges) for an object.

Parameters:

Name Type Description Default
root_id int

Object root ID to look up.

required
filtered bool

Whether to filter the change log to only include splits and merges which affect the final state of the object (filtered=True), as opposed to including edit history for objects which as some point were split from the query object root_id (filtered=False). Defaults to True.

True

Returns:

Type Description
dict

Dictionary summarizing split and merge events in the object history, containing the following keys:

  • "n_merges": int
    • Number of merges
  • "n_splits": int
    • Number of splits
  • "operations_ids": list of int
    • Identifiers for each operation
  • "past_ids": list of int
    • Previous root ids for this object
  • "user_info": dict of dict
    • Dictionary keyed by user (string) to a dictionary specifying how many merges and splits that user performed on this object

get_user_operations(user_id, timestamp_start, include_undo=True, timestamp_end=None)

Get operation details for a user ID. Currently, this is only available to admins.

Parameters:

Name Type Description Default
user_id int

User ID to query (use 0 for all users (admin only)).

required
timestamp_start datetime

Timestamp to start filter (UTC).

required
include_undo bool

Whether to include undos. Defaults to True.

True
timestamp_end datetime

Timestamp to end filter (UTC). Defaults to now.

None

Returns:

Type Description
DataFrame

DataFrame including the following columns:

  • "operation_id": int
    • Identifier for the operation.
  • "timestamp": datetime.datetime
    • Timestamp of the operation.
  • "user_id": int
    • User who performed the operation.

get_tabular_change_log(root_ids, filtered=True)

Get a detailed changelog for neurons.

Parameters:

Name Type Description Default
root_ids list of int

Object root IDs to look up.

required
filtered bool

Whether to filter the change log to only include splits and merges which affect the final state of the object (filtered=True), as opposed to including edit history for objects which as some point were split from the query objects in root_ids (filtered=False). Defaults to True.

True

Returns:

Type Description
dict of pd.DataFrame

The keys are the root IDs, and the values are DataFrames with the following columns and datatypes:

  • "operation_id": int
    • Identifier for the operation.
  • "timestamp": int
    • Timestamp of the operation, provided in milliseconds. To convert to datetime, use datetime.datetime.utcfromtimestamp(timestamp/1000).
  • "user_id": int
    • User who performed the operation.
  • "before_root_ids: list of int
    • Root IDs of objects that existed before the operation.
  • "after_root_ids: list of int
    • Root IDs of objects created by the operation. Note that this only records the root id that was kept as part of the query object, so there will only be one in this list.
  • "is_merge": bool
    • Whether the operation was a merge.
  • "user_name": str
    • Name of the user who performed the operation.
  • "user_affiliation": str
    • Affiliation of the user who performed the operation.

get_leaves_many(root_ids, bounds=None, stop_layer=None)

Get all supervoxels for a list of root IDs.

Parameters:

Name Type Description Default
root_ids Iterable

Root IDs to query.

required
bounds

If specified, returns supervoxels within a 3x2 numpy array of bounds [[minx,maxx],[miny,maxy],[minz,maxz]]. If None, finds all supervoxels.

None
stop_layer int

If specified, returns chunkedgraph nodes at layer stop_layer default will be stop_layer=1 (supervoxels).

None

Returns:

Type Description
dict

Dict relating ids to contacts

get_leaves(root_id, bounds=None, stop_layer=None)

Get all supervoxels for a root ID.

Parameters:

Name Type Description Default
root_id int

Root ID to query.

required
bounds

If specified, returns supervoxels within a 3x2 numpy array of bounds [[minx,maxx],[miny,maxy],[minz,maxz]]. If None, finds all supervoxels.

None
stop_layer int

If specified, returns chunkedgraph nodes at layer stop_layer default will be stop_layer=1 (supervoxels).

None

Returns:

Type Description
np.array of np.int64

Array of supervoxel IDs (or node ids if stop_layer>1).

do_merge(supervoxels, coords, resolution=(4, 4, 40))

Perform a merge on the chunked graph.

Parameters:

Name Type Description Default
supervoxels iterable

An N-long list of supervoxels to merge.

required
coords array

An Nx3 array of coordinates of the supervoxels in units of resolution.

required
resolution tuple

What to multiply coords by to get nanometers. Defaults to (4,4,40).

(4, 4, 40)

undo_operation(operation_id)

Undo an operation.

Parameters:

Name Type Description Default
operation_id int

Operation ID to undo.

required

Returns:

Type Description
dict

execute_split(source_points, sink_points, root_id, source_supervoxels=None, sink_supervoxels=None)

Execute a multicut split based on points or supervoxels.

Parameters:

Name Type Description Default
source_points array or list

Nx3 list or array of 3d points in nm coordinates for source points (red).

required
sink_points array or list

Mx3 list or array of 3d points in nm coordinates for sink points (blue).

required
root_id int

Root ID of object to do split preview.

required
source_supervoxels (array, list or None)

If providing source supervoxels, an N-length array of supervoxel IDs or Nones matched to source points. If None, treats as a full array of Nones. By default None.

None
sink_supervoxels (array, list or None)

If providing sink supervoxels, an M-length array of supervoxel IDs or Nones matched to source points. If None, treats as a full array of Nones. By default None.

None

Returns:

Name Type Description
operation_id int

Unique ID of the split operation

new_root_ids list of int

List of new root IDs resulting from the split operation.

preview_split(source_points, sink_points, root_id, source_supervoxels=None, sink_supervoxels=None, return_additional_ccs=False)

Get supervoxel connected components from a preview multicut split.

Parameters:

Name Type Description Default
source_points array or list

Nx3 list or array of 3d points in nm coordinates for source points (red).

required
sink_points array or list

Mx3 list or array of 3d points in nm coordinates for sink points (blue).

required
root_id int

Root ID of object to do split preview.

required
source_supervoxels (array, list or None)

If providing source supervoxels, an N-length array of supervoxel IDs or Nones matched to source points. If None, treats as a full array of Nones. By default None.

None
sink_supervoxels (array, list or None)

If providing sink supervoxels, an M-length array of supervoxel IDs or Nones matched to source points. If None, treats as a full array of Nones. By default None.

None
return_additional_ccs bool

If True, returns any additional connected components beyond the ones with source and sink points. In most situations, this can be ignored. By default, False.

False

Returns:

Name Type Description
source_connected_component list

Supervoxel IDs in the component with the most source points.

sink_connected_component list

Supervoxel IDs in the component with the most sink points.

successful_split bool

True if the split worked.

other_connected_components (optional) : list of lists of int

List of lists of supervoxel IDs for any other resulting connected components. Only returned if return_additional_ccs is True.

get_children(node_id)

Get the children of a node in the chunked graph hierarchy.

Parameters:

Name Type Description Default
node_id int

Node ID to query.

required

Returns:

Type Description
np.array of np.int64

IDs of child nodes.

get_contact_sites(root_id, bounds, calc_partners=False)

Get contacts for a root ID.

Parameters:

Name Type Description Default
root_id int

Root ID to query.

required
bounds

Bounds within a 3x2 numpy array of bounds [[minx,maxx],[miny,maxy],[minz,maxz]] for which to find contacts. Running this query without bounds is too slow.

required
calc_partners bool

If True, get partner root IDs. By default, False.

False

Returns:

Type Description
dict

Dict relating ids to contacts

find_path(root_id, src_pt, dst_pt, precision_mode=False)

Find a path between two locations on a root ID using the level 2 chunked graph.

Parameters:

Name Type Description Default
root_id int

Root ID to query.

required
src_pt array

3-element array of xyz coordinates in nm for the source point.

required
dst_pt array

3-element array of xyz coordinates in nm for the destination point.

required
precision_mode bool

Whether to perform the search in precision mode. Defaults to False.

False

Returns:

Name Type Description
centroids_list array

Array of centroids along the path.

l2_path np.array of int

Array of level 2 chunk IDs along the path.

failed_l2_ids np.array of int

Array of level 2 chunk IDs that failed to find a path.

get_subgraph(root_id, bounds)

Get subgraph of root id within a bounding box.

Parameters:

Name Type Description Default
root_id int

Root (or any node ID) of chunked graph to query.

required
bounds array

3x2 bounding box (x,y,z) x (min,max) in chunked graph coordinates.

required

Returns:

Type Description
np.array of np.int64

Node IDs in the subgraph.

np.array of np.double

Affinities of edges in the subgraph.

np.array of np.int32

Areas of nodes in the subgraph.

level2_chunk_graph(root_id, bounds=None)

Get graph of level 2 chunks, the smallest agglomeration level above supervoxels.

Parameters:

Name Type Description Default
root_id int

Root id of object

required
bounds array

3x2 bounding box (x,y,z) x (min,max) in chunked graph coordinates (use client.chunkedgraph.base_resolution to view this default resolution for your chunkedgraph client). Note that the result will include any level 2 nodes which have chunk boundaries within some part of this bounding box, meaning that the representative point for a given level 2 node could still be slightly outside of these bounds. If None, returns all level 2 chunks for the root ID.

None

Returns:

Type Description
list of list

Edge list for level 2 chunked graph. Each element of the list is an edge, and each edge is a list of two node IDs (source and target).

remesh_level2_chunks(chunk_ids)

Submit specific level 2 chunks to be remeshed in case of a problem.

Parameters:

Name Type Description Default
chunk_ids list

List of level 2 chunk IDs.

required

get_operation_details(operation_ids)

Get the details of a list of operations.

Parameters:

Name Type Description Default
operation_ids Iterable[int]

List/array of operation IDs.

required

Returns:

Type Description
dict of str to dict

A dict of dicts of operation info, keys are operation IDs (as strings), values are a dictionary of operation info for the operation. These dictionaries contain the following keys:

  • "added_edges"/"removed_edges": list of list of int
    • List of edges added (if a merge) or removed (if a split) by this operation. Each edge is a list of two supervoxel IDs (source and target).
  • "roots": list of int
    • List of root IDs that were created by this operation.
  • "sink_coords": list of list of int
    • List of sink coordinates for this operation. The sink is one of the points placed by the user when specifying the operation. Each sink coordinate is a list of three integers (x, y, z), corresponding to spatial coordinates in segmentation voxel space.
  • "source_coords": list of list of int
    • List of source coordinates for this operation. The source is one of the points placed by the user when specifying the operation. Each source coordinate is a list of three integers (x, y, z), corresponding to spatial coordinates in segmentation voxel space.
  • "timestamp": str
    • Timestamp of the operation.
  • "user": str
    • User ID number who performed the operation (as a string).

get_lineage_graph(root_id, timestamp_past=None, timestamp_future=None, as_nx_graph=False, exclude_links_to_future=False, exclude_links_to_past=False)

Returns the lineage graph for a root ID, optionally cut off in the past or the future.

Each change in the chunked graph creates a new root ID for the object after that change. This function returns a graph of all root IDs for a given object, tracing the history of the object in terms of merges and splits.

Parameters:

Name Type Description Default
root_id int

Object root ID.

required
timestamp_past datetime or None

Cutoff for the lineage graph backwards in time. By default, None.

None
timestamp_future datetime or None

Cutoff for the lineage graph going forwards in time. By default, uses the timestamp property for this client, which defaults to the current time.

None
as_nx_graph

If True, a NetworkX graph is returned.

False
exclude_links_to_future

If True, links from nodes before timestamp_future to after timestamp_future are removed. If False, the link(s) which has one node before timestamp and one node after timestamp is kept.

False
exclude_links_to_past

If True, links from nodes before timestamp_past to after timestamp_past are removed. If False, the link(s) which has one node before timestamp and one node after timestamp is kept.

False

Returns:

Type Description
dict

Dictionary describing the lineage graph and operations for the root ID. Not returned if as_nx_graph is True. The dictionary contains the following keys:

  • "directed" : bool
    • Whether the graph is directed.
  • "graph" : dict
    • Dictionary of graph attributes.
  • "links" : list of dict
    • Each element of the list is a dictionary describing an edge in the lineage graph as "source" and "target" keys.
  • "multigraph" : bool
    • Whether the graph is a multigraph.
  • "nodes" : list of dict
    • Each element of the list is a dictionary describing a node in the lineage graph, usually with "id", "timestamp", and "operation_id" keys.
DiGraph

NetworkX directed graph of the lineage graph. Only returned if as_nx_graph is True.

get_latest_roots(root_id, timestamp=None, timestamp_future=None)

Returns root IDs that are related to the given root_id at a given timestamp. Can be used to find the "latest" root IDs associated with an object.

Parameters:

Name Type Description Default
root_id int

Object root ID.

required
timestamp datetime or None

Timestamp of where to query IDs from. If None, uses the timestamp property for this client, which defaults to the current time.

None
timestamp_future datetime or None

DEPRECATED name, use timestamp instead. Timestamp to suggest IDs from (note can be in the past relative to the root). By default, None.

None

Returns:

Type Description
ndarray

1d array with all latest successors.

get_original_roots(root_id, timestamp_past=None)

Returns root IDs that are the latest successors of a given root ID.

Parameters:

Name Type Description Default
root_id int

Object root ID.

required
timestamp_past datetime or None

Cutoff for the search going backwards in time. By default, None.

None

Returns:

Type Description
ndarray

1d array with all latest successors.

is_latest_roots(root_ids, timestamp=None)

Check whether these root IDs are still a root at this timestamp.

Parameters:

Name Type Description Default
root_ids array-like of int

Root IDs to check.

required
timestamp datetime

Timestamp to check whether these IDs are valid root IDs in the chunked graph. If None, uses the timestamp property for this client, which defaults to the current time.

None

Returns:

Type Description
np.array of bool

Array of whether these are valid root IDs.

suggest_latest_roots(root_id, timestamp=None, stop_layer=None, return_all=False, return_fraction_overlap=False)

Suggest latest roots for a given root id, based on overlap of component chunk IDs. Note that edits change chunk IDs, and so this effectively measures the fraction of unchanged chunks at a given chunk layer, which sets the size scale of chunks. Higher layers are coarser.

Parameters:

Name Type Description Default
root_id int

Root ID of the potentially outdated object.

required
timestamp datetime

Datetime at which "latest" roots are being computed, by default None. If None, uses the timestamp property for this client, which defaults to the current time. Note that this has to be a timestamp after the creation of the root_id.

None
stop_layer int

Chunk level at which to compute overlap, by default None. No value will take the 4th from the top layer, which emphasizes speed and works well for larger objects. Lower values are slower but more fine-grained. Values under 2 (i.e. supervoxels) are not recommended except in extremely fine grained scenarios.

None
return_all bool

If True, return all current IDs sorted from most overlap to least, by default False. If False, only the top is returned.

False
return_fraction_overlap bool

If True, return all fractions sorted by most overlap to least, by default False. If False, only the top value is returned.

False

is_valid_nodes(node_ids, start_timestamp=None, end_timestamp=None)

Check whether nodes are valid for given timestamp range.

Valid is defined as existing in the chunked graph. This makes no statement about these IDs being roots, supervoxel or anything in-between. It also does not take into account whether a root ID has since been edited.

Parameters:

Name Type Description Default
node_ids array-like of int

Node IDs to check.

required
start_timestamp datetime

Timestamp to check whether these IDs were valid after this timestamp. Defaults to None (assumes now).

None
end_timestamp datetime

Timestamp to check whether these IDs were valid before this timestamp. If None, uses the timestamp property for this client, which defaults to the current time.

None

Returns:

Type Description
np.array of bool

Array of whether these are valid IDs.

get_root_timestamps(root_ids, latest=False, timestamp=None)

Retrieves timestamps when roots where created.

Parameters:

Name Type Description Default
root_ids

Iterable of root IDs to query.

required
latest bool

If False, returns the first timestamp that the root_id was valid for each root ID. If True, returns the newest/latest timestamp for each root ID. Note, this will return the timestamp at which the query was run when the root is currently valid. This means that you will get a different answer if you make this same query at a later time if you don't specify a timestamp parameter.

False
timestamp datetime

Timestamp to query when using latest=True. Use this to provide consistent results for a particular timestamp. If an ID is still valid at a point in the future past this timestamp, the query will still return this timestamp as the latest moment in time. An error will occur if you provide a timestamp for which the root ID is not valid. If None, uses the timestamp property for this client, which defaults to the current time.

None

Returns:

Type Description
np.array of datetime.datetime

Array of timestamps when root_ids were created.

get_past_ids(root_ids, timestamp_past=None, timestamp_future=None)

For a set of root IDs, get the list of IDs at a past or future time point that could contain parts of the same object.

Parameters:

Name Type Description Default
root_ids Iterable of int

Iterable of root IDs to query.

required
timestamp_past datetime or None

Time of a point in the past for which to look up root ids. Default is None.

None
timestamp_future datetime or None

Time of a point in the future for which to look up root ids. Not implemented on the server currently. Default is None.

None

Returns:

Type Description
dict

Dict with keys "future_id_map" and "past_id_map". Each is a dict whose keys are the supplied root_ids and whose values are the list of related root IDs at timestamp_past/timestamp_future.

get_delta_roots(timestamp_past, timestamp_future=datetime.datetime.now(datetime.timezone.utc))

Get the list of roots that have changed between timetamp_past and timestamp_future.

Parameters:

Name Type Description Default
timestamp_past datetime

Past timepoint to query

required
timestamp_future datetime

Future timepoint to query. Defaults to datetime.datetime.now(datetime.timezone.utc).

now(utc)

Returns:

Name Type Description
old_roots np.ndarray of np.int64

Roots that have expired in that interval.

new_roots np.ndarray of np.int64

Roots that are new in that interval.

get_oldest_timestamp()

Get the oldest timestamp in the database.

Returns:

Type Description
datetime

Oldest timestamp in the database.